Protein tyrosine phosphatase regulation of stem and progenitor cell biology
作者： Veronique Dubreuil , Jan Sap , Sheila Harroch
DOI: 10.1016/J.SEMCDB.2014.09.012
关键词: Cell biology 、 Protein tyrosine phosphatase 、 Cellular activity 、 Fibroblast growth factor receptor 、 Stem cell biology 、 Signal transduction 、 Progenitor cell 、 Biology 、 Stem cell
摘要: This review surveys the contributions of protein tyrosine phosphatases (PTPs) to maintenance and differentiation stem progenitor cells. A diverse family PTPs acts at multiple steps signaling cascades cellular locales. Their activities as modifiers provide another layer integration pathways, which functionally link activity ultimately converge into regulation cell fates. The development agents targeting is a growing endeavor that will benefit biology offer promising therapeutic strategies.
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