作者: Eugene B. Hanlon , Donald F. Siwek , Ann C. Mckee , Neil W. Kowall , Hui Fang
DOI: 10.1364/BIO.2004.WC1
关键词: Pathology 、 Light propagation 、 Particle scattering 、 Materials science 、 Mie scattering 、 In vivo 、 Spectroscopy 、 Diffuse reflection 、 Protein aggregation 、 Light scattering 、 Nuclear magnetic resonance
摘要: Neurodegenerative pathologies such as Alzheimer's disease present protein aggregates that scatter light. We are developing techniques to detect their characteristic spectra in vivo a basis for definitive, non-invasive diagnosis and monitoring experimental therapeutics.