The fundamental role of bone morphogenetic protein 15 in ovarian function and its involvement in female fertility disorders

作者: Luca Persani , Raffaella Rossetti , Elisa Di Pasquale , Chiara Cacciatore , Stéphane Fabre

DOI: 10.1093/HUMUPD/DMU036

关键词: BioinformaticsEndocrinologyOvarian reservePolycystic ovaryOvarian follicleInternal medicineGranulosa cellFolliculogenesisOvulationGrowth differentiation factor-9Bone morphogenetic protein 15Biology

摘要: BACKGROUND A large number of studies have contributed to understanding the general mechanisms driving ovarian folliculogenesis in humans and show a complex endocrine dialog …

参考文章(151)
Mourad Assidi, Isabelle Dufort, Atef Ali, Mélanie Hamel, Omran Algriany, Steph Dielemann, Marc-André Sirard, Identification of Potential Markers of Oocyte Competence Expressed in Bovine Cumulus Cells Matured with Follicle-Stimulating Hormone and/or Phorbol Myristate Acetate In Vitro Biology of Reproduction. ,vol. 79, pp. 209- 222 ,(2008) , 10.1095/BIOLREPROD.108.067686
Noora Kaivo-Oja, Jonas Bondestam, Meerit Kämäräinen, Janne Koskimies, Ursula Vitt, Mark Cranfield, Kaisa Vuojolainen, Janne P. Kallio, Vesa M. Olkkonen, Masaru Hayashi, Aristidis Moustakas, Nigel P. Groome, Peter ten Dijke, Aaron J. W. Hsueh, Olli Ritvos, Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells. The Journal of Clinical Endocrinology and Metabolism. ,vol. 88, pp. 755- 762 ,(2003) , 10.1210/JC.2002-021317
Caroline S Hill, TGF-β signalling pathways in early Xenopus development Current Opinion in Genetics & Development. ,vol. 11, pp. 533- 540 ,(2001) , 10.1016/S0959-437X(00)00229-X
S Elis, J Dupont, I Couty, L Persani, M Govoroun, E Blesbois, F Batellier, P Monget, Expression and biological effects of bone morphogenetic protein-15 in the hen ovary. Journal of Endocrinology. ,vol. 194, pp. 485- 497 ,(2007) , 10.1677/JOE-07-0143
Seiji Saito, Keiichi Yano, Shweta Sharma, Heather E. McMahon, Shunichi Shimasaki, Characterization of the post-translational modification of recombinant human BMP-15 mature protein. Protein Science. ,vol. 17, pp. 362- 370 ,(2008) , 10.1110/PS.073232608
D. G. Mottershead, L. J. Ritter, R. B. Gilchrist, Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15 Molecular Human Reproduction. ,vol. 18, pp. 121- 128 ,(2012) , 10.1093/MOLEHR/GAR056
James P. Hanrahan, Scott M. Gregan, Philippe Mulsant, Michael Mullen, George H. Davis, Richard Powell, Susan M. Galloway, Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries) Biology of Reproduction. ,vol. 70, pp. 900- 909 ,(2004) , 10.1095/BIOLREPROD.103.023093
Ali Hemmati-Brivanlou, Giorgio Lagna, Paul A. Wilson, Atsushi Suzuki, Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1 Development. ,vol. 124, pp. 3177- 3184 ,(1997) , 10.1242/DEV.124.16.3177