Direction of Movement Is Encoded in the Human Primary Motor Cortex
作者： Carolien M. Toxopeus , Bauke M. de Jong , Gopal Valsan , Bernard A. Conway , Klaus L. Leenders
DOI: 10.1371/JOURNAL.PONE.0027838
关键词: Neuronal tuning 、 Anatomy 、 Motor control 、 Primary motor cortex 、 Horizontal axis 、 Physics 、 Movement (music) 、 Functional magnetic resonance imaging 、 Posterior parietal cortex 、 Motor cortex 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: The present study investigated how direction of hand movement, which is a well-described parameter in cerebral organization motor control, incorporated the somatotopic representation manual effector system human primary cortex (M1). Using functional magnetic resonance imaging (fMRI) and step-tracking task we found that activation patterns related to movement different directions were spatially disjoint within area on M1. Foci specific segregated M1 area; 0° (right) was located most laterally/superficially, whereas 180° (left) 270° (down) elicited more medially area. Activation 90° between other directions. Moreover, by investigating differences activations along horizontal (0°+180°) vertical (90°+270°) axis, axis anterolaterally/dorsally than for supporting individual are direction- not muscle related. Our results direction-related accordance with findings recent fMRI studies neural encoding thus provide further evidence direct link as an organizational principle sensorimotor transformation execution coded representations
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