Membrane Trafficking in Nerve Terminals

摘要: Publisher Summary Most exocytotic release of neurotransmitters occurs in the nerve terminal, which can be envisaged as a dedicated secretory compartment. Thus, terminal is most interesting compartment from point view membrane trafficking, also because it indirectly involved large part trafficking events occurring other neuronal compartments; membrane-bound organelles found axons are actually traveling to or ending, and sorting proteins destined exocytosis endings major task Golgi complex. In recent times, intense research on mechanism neurotransmitter has been done. The basic features process shared with kinds exocytosis, such synaptic vesicles—mechanisms fusion. Membrane fusion ubiquitous characterizing traffic among various intracellular compartments plasma membrane. regulated must governed so that triggered only response specific stimulus. Two possibilities exist: either biological membranes keen fuse each have ability keep this spontaneous under control intrinsically resistant fusing therefore constitutive intervention proteins. This chapter describes life cycle storage at level, underlining cells well those peculiar cells.