Cobalt, nickel and iron embedded chitosan microparticles as efficient and reusable catalysts for Heck cross-coupling reactions.

摘要: Abstract Cobalt, nickel and iron are efficient catalysts for numerous chemical biological reactions, but they hardly immobilized on solid matrixes due to their relatively weak chelation with the surface molecules. We have employed a co-electrospraying coupling glutaraldehyde cross-linking technique prepare cobalt (Co2+), (Ni2+) (Fe2+) catalyst embedded chitosan microparticles (M@MicroCS) (M = Co, Ni Fe). The Co@MicroCS beads exhibited excellent catalytic activity Heck cross-coupling reactions of aromatic iodides alkenes. Moreover, bead could be even reused at least five times without significant loss activities. average diameter free volume holes porous was determined much larger than size reactant product molecules, allowing them freely migrate through sites inside beads. These results clearly indicate that catalyzed by primarily occurs Taken together, we demonstrated straightforward approach recyclable heterogeneous derived from first-row transition metal entrapping microparticles.