Detectors for Trace Organic Analysis by Liquid Chromatography: Principles and Applications

作者: Peter T. Kissinger , Lawrence J. Felice , David J. Miner , Carl R. Preddy , Ronald E. Shoup

DOI: 10.1007/978-1-4615-6731-8_3

关键词: Precolumn derivatizationDetectorVolatility (chemistry)ChromatographyThermal stabilityChemical separationMaterials scienceRoutine analysisChemical ionizationLiquid column

摘要: Although liquid column chromatography (LC) had been used as a means of chemical separation for many years prior to 1969, it was not accepted method useful rapid, routine analysis, due the relatively long times required achieve resolution. Significant theoretical and technological advances have since made in this field, excellent separations can now be achieved within few minutes using high-efficiency LC packings. Liquid offers advantages over gas-liquid (GLC) that no restrictions are placed on size, volatility, or thermal stability sample molecules. In addition, tremendous flexibility choice mobile stationary phases such most components conveniently resolved some appropriate combination phases.

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