Clinical Aspects of Medullary Thyroid Carcinoma
作者： Douglas W. Ball
DOI: 10.1007/978-1-59259-995-0_70
关键词: Thyroid cancer 、 Thyroid carcinoma 、 Pathology 、 Medullary cavity 、 Serum calcitonin 、 Neoplasm 、 Thyroid 、 Medicine 、 Medullary thyroid cancer
摘要: Medullary thyroid cancer (MTC), an uncommon neoplasm stemming from the calcitonin-producing parafollicular C cells, represents approximately 5% of cases. Unique among all types is close association MTC with inherited tumor syndromes in about 20% patients. Activating mutations ret proto-oncogene account for hereditary basis and contribute significantly to sporadic development as well. These findings have a major impact on diagnosis therapy MTC.
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