Biomarkers of Individual Foods, and Separation of Diets Using Untargeted LC–MS‐based Plasma Metabolomics in a Randomized Controlled Trial

作者: Evrim Acar , Gözde Gürdeniz , Bekzod Khakimov , Francesco Savorani , Sanne Kellebjerg Korndal

DOI: 10.1002/MNFR.201800215

关键词: HydroxyprolineCarnitinePipecolic acidMetabolomicsBetaineArea under the curveMetabolomeMetaboliteFood scienceChemistry

摘要: … The major discriminatory features between the NND and the ADD in the present study on plasma metabolite profiles by LC–MS mainly reflect the foods contrasting between the diets and…

参考文章(39)
Carsten Kuhl, Ralf Tautenhahn, Christoph Böttcher, Tony R. Larson, Steffen Neumann, CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets. Analytical Chemistry. ,vol. 84, pp. 283- 289 ,(2012) , 10.1021/AC202450G
Lloyd W Sumner, Alexander Amberg, Dave Barrett, Michael H Beale, Richard Beger, Clare A Daykin, Teresa W-M Fan, Oliver Fiehn, Royston Goodacre, Julian L Griffin, Thomas Hankemeier, Nigel Hardy, James Harnly, Richard Higashi, Joachim Kopka, Andrew N Lane, John C Lindon, Philip Marriott, Andrew W Nicholls, Michael D Reily, John J Thaden, Mark R Viant, et al., Proposed minimum reporting standards for chemical analysis Metabolomics. ,vol. 3, pp. 211- 221 ,(2007) , 10.1007/S11306-007-0082-2
V. Adamsson, A. Reumark, I.-B. Fredriksson, E. Hammarström, B. Vessby, G. Johansson, U. Risérus, Effects of a healthy Nordic diet on cardiovascular risk factors in hypercholesterolaemic subjects: a randomized controlled trial (NORDIET) Journal of Internal Medicine. ,vol. 269, pp. 150- 159 ,(2011) , 10.1111/J.1365-2796.2010.02290.X
Julie A Schmidt, Sabina Rinaldi, Pietro Ferrari, Marion Carayol, David Achaintre, Augustin Scalbert, Amanda J Cross, Marc J Gunter, Georgina K Fensom, Paul N Appleby, Timothy J Key, Ruth C Travis, Metabolic profiles of male meat eaters, fish eaters, vegetarians, and vegans from the EPIC-Oxford cohort The American Journal of Clinical Nutrition. ,vol. 102, pp. 1518- 1526 ,(2015) , 10.3945/AJCN.115.111989
Colin A. Smith, Elizabeth J. Want, Grace O'Maille, Ruben Abagyan, Gary Siuzdak, XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Analytical Chemistry. ,vol. 78, pp. 779- 787 ,(2006) , 10.1021/AC051437Y
Cristina Menni, Guangju Zhai, Alexander MacGregor, Cornelia Prehn, Werner Römisch-Margl, Karsten Suhre, Jerzy Adamski, Aedin Cassidy, Thomas Illig, Tim D. Spector, Ana M. Valdes, Targeted metabolomics profiles are strongly correlated with nutritional patterns in women Metabolomics. ,vol. 9, pp. 506- 514 ,(2013) , 10.1007/S11306-012-0469-6
Gözde Gürdeniz, Louise Hansen, Morten Arendt Rasmussen, Evrim Acar, Anja Olsen, Jane Christensen, Thaer Barri, Anne Tjønneland, Lars Ove Dragsted, Patterns of time since last meal revealed by sparse PCA in an observational LC–MS based metabolomics study Metabolomics. ,vol. 9, pp. 1073- 1081 ,(2013) , 10.1007/S11306-013-0525-X
Emma Peré-Trepat, Alastair B. Ross, François-Pierre Martin, Serge Rezzi, Sunil Kochhar, Ann Louise Hasselbalch, Kirsten O. Kyvik, Thorkild I.A. Sørensen, Chemometric strategies to assess metabonomic imprinting of food habits in epidemiological studies Chemometrics and Intelligent Laboratory Systems. ,vol. 104, pp. 95- 100 ,(2010) , 10.1016/J.CHEMOLAB.2010.06.001
Ji Young Kim, Ju Yeon Park, Oh Yoen Kim, Bo Mi Ham, Hyun-Jin Kim, Dae Young Kwon, Yangsoo Jang, Jong Ho Lee, Metabolic profiling of plasma in overweight/obese and lean men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC-Q-TOF MS). Journal of Proteome Research. ,vol. 9, pp. 4368- 4375 ,(2010) , 10.1021/PR100101P