Consequences of acute myelogenous leukemia in early pregnancy

作者: J. S. Lilleyman , A. S. Hill , K. J. Anderton

DOI: 10.1002/1097-0142(197709)40:3<1300::AID-CNCR2820400345>3.0.CO;2-9

关键词: Early pregnancy factorLeukemiaComplete remissionPregnancyCytarabineMedicineVincristinePediatricsMyelogenousAcute myelomonocytic leukemiaImmunologyCancer researchOncology

摘要: Cytarabine and thioguanine therapy for acute myelomonocytic leukemia initiated in the tenth week of pregnancy (with addition vincristine rubidomycin at 17 weeks) led to a short complete remission 24-year-old primigravida. This is first case be reported which cytarabine was administered trimester prostaglandin termination performed 20 weeks produced an apparently normal fetus. A review literature suggests slightly less than 50% chance producing live healthy baby if myelogenous diagnosed half pregnancy, with materna mortality approaching 100% by six months postpartum. Current may improve these figures.

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