From Asilomar to Genome Editing: Research Ethics and Models of Decision

摘要: The aim of the presentation is to focus on differences between two scientific contexts: genetic engineering context 1970s, with specific attention paid use recombinant DNA technique generate genetically modified molecules, and current genome editing context, CRISPR-Cas9 technology modify human germ line cells genetically. In both events, scientists have been involved in discussions that gone beyond mere professional deontology touching policy issues such as freedom research, responsibility for consequences right public participate evaluation goals research methods, relationship cost benefit possible social consequences. comparison these contexts suggests need handling by defining procedures meet criteria democracy towards society. underlying objective should be effectively launch actions interventions based not a hierarchical approach but rather reticular conception knowledge.