Guideline adherence in antithrombotic treatment after concomitant ablation surgery in atrial fibrillation patients

作者: Henrica NAM van Breugel , Sandro Gelsomino , Pieter WJ Lozekoot , Ryan E Accord , Fabiana Lucà

DOI: 10.1093/ICVTS/IVT522

关键词: GuidelineSinus rhythmPreoperative careSurgeryConcomitantAtrial fibrillationStrokeFibrinolytic agentProspective cohort studyMedicine

摘要: OBJECTIVES: We investigated real-life oral anticoagulation (OAC) treatment after surgical ablation and examined its adherence to current recommendations. also explored factors related OAC use preoperatively at follow-up. METHODS: One hundred fifteen patients with atrial fibrillation (AF) were evaluated during 12-month follow-up surgery. Patients divided into two categories according the congestive heart failure, hypertension, age ≥75 years, diabetes prior stroke [or transient ischaemic attack or thromboembolism] (CHADS2) score: 60 assigned high-risk group (CHADS2 score ≥2) 55 low-risk ≤1). was defined as guideline adherent, undertreatment overtreatment. RESULTS: Baseline overall 62%. underprescribed in overprescribed (both, P 75 years (P= 0.01) preoperative AF > paroxysmal 0.013). Overall showed a trend towards better sinus rhythm (SR) subgroup (74% vs 55%, P= 0.02). (both P< 0.001). After logistic regression analysis, 0.007) other indications for predictors of treatment. CONCLUSIONS: Real-life prescription moderate adherence, being undertreated overtreated. These findings stress importance that antithrombotic undergoing surgery needs be critically re-evaluated.

参考文章(28)
Gerhard Hindricks, Hans Kottkamp, Philipp Sommer, Thomas Gaspar, Kerstin Bode, Arash Arya, Loukianos S. Rallidis, Dimitrios Th. Kremastinos, Christopher Piorkowski, Nikolaos Dagres, Real-life anticoagulation treatment of atrial fibrillation after catheter ablation: Possible overtreatment of low-risk patients. Thrombosis and Haemostasis. ,vol. 102, pp. 754- 758 ,(2009) , 10.1160/TH09-03-0184
Jeffrey L. Anderson, Jonathan L. Halperin, Nancy M. Albert, Biykem Bozkurt, Ralph G. Brindis, Lesley H. Curtis, David DeMets, Robert A. Guyton, Judith S. Hochman, Richard J. Kovacs, E. Magnus Ohman, Susan J. Pressler, Frank W. Sellke, Win-Kuang Shen, Management of Patients With Atrial Fibrillation (Compilation of 2006 ACCF/AHA/ESC and 2011 ACCF/AHA/HRS Recommendations) A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Journal of the American College of Cardiology. ,vol. 61, pp. 1916- 1926 ,(2013) , 10.1161/CIR.0B013E318290826D
Margaret C Fang, Alan S Go, Yuchiao Chang, Leila Borowsky, Niela K Pomernacki, Daniel E Singer, ATRIA Study Group, Comparison of Risk Stratification Schemes to Predict Thromboembolism in People With Nonvalvular Atrial Fibrillation Journal of the American College of Cardiology. ,vol. 51, pp. 810- 815 ,(2008) , 10.1016/J.JACC.2007.09.065
Robert McBane, David Hodge, Waldemar Wysokinski, Clinical and echocardiographic measures governing thromboembolism destination in atrial fibrillation. Thrombosis and Haemostasis. ,vol. 99, pp. 951- 955 ,(2008) , 10.1160/TH07-12-0734
Robby Nieuwlaat, S Bertil Olsson, Gregory YH Lip, A John Camm, Günter Breithardt, Alessandro Capucci, Joan G Meeder, Martin H Prins, Samuel Lévy, Harry JGM Crijns, Euro Heart Survey Investigators, Guideline-adherent antithrombotic treatment is associated with improved outcomes compared with undertreatment in high-risk patients with atrial fibrillation. The Euro Heart Survey on Atrial Fibrillation American Heart Journal. ,vol. 153, pp. 1006- 1012 ,(2007) , 10.1016/J.AHJ.2007.03.008
Emilia Antonucci, Elisa Grifoni, Rosanna Abbate, Gian Franco Gensini, Domenico Prisco, Daniela Poli, Stroke risk in atrial fibrillation patients on warfarin Predictive ability of risk stratification schemes for primary and secondary prevention Thrombosis and Haemostasis. ,vol. 101, pp. 367- 372 ,(2009) , 10.1160/TH08-09-0592
Gregory Lip, Deirdre Lane, Female gender is a risk factor for stroke and thromboembolism in atrial fibrillation patients. Thrombosis and Haemostasis. ,vol. 101, pp. 802- 805 ,(2009) , 10.1160/TH09-02-0106
Daniela Poli, Emilia Antonucci, Elisa Grifoni, Rosanna Abbate, Gian Franco Gensini, Domenico Prisco, Bleeding Risk During Oral Anticoagulation in Atrial Fibrillation Patients Older Than 80 Years Journal of the American College of Cardiology. ,vol. 54, pp. 999- 1002 ,(2009) , 10.1016/J.JACC.2009.05.046