Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innate-defense capacity in healthy middle-aged people.

摘要: Different lactic acid bacteria have often been administered as a dietary means to enhance immune system activity. Based on this statement, the aim of current work was test effects Lactobacillus casei DN114001 fermented milk consumption response capacity in middle-age volunteers. Forty-five healthy volunteers, 24 women and 21 men (aged: 51–58 years), were randomized into two groups receive three cups per day L. (108–1010 ufc/g) (n=23), or placebo (n=22), during an 8-week period. Measurements performed before (day 0), after nutritional intervention 56). After trial, no changes cell proportions detected, but probiotic-treated group increased oxidative burst monocytes (probiotic group: p=0.029; p=0.625), well NK cells tumoricidal activity p=0.023; p=0.125). Results showed that daily intake containing could positive effect modulating innate defense healthy-middle-age people.