Coated particles for sustained-release pharmaceutical administration
作者： Thomas J. Smith
DOI:
关键词: Microparticle 、 Chemical engineering 、 Materials science 、 Core (manufacturing) 、 Active ingredient 、 Composite material 、 Coating
摘要: Coated microparticles for sustained-release of an active pharmaceutical ingredient after parenteral administration, and methods producing such coated microparticles, are provided. The comprise core particles a first polymeric coating on the particles. is permeable to forms saturated solution within microparticle, resulting in pseudo-zero-sustained release period. A second can be employed add mechanical support or as rate-controlling element.
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