Optimized algorithm for Sanger sequencing-based EGFR mutation analyses in NSCLC biopsies

作者: Christine Sers , Jürgen R. Fischer , Michael Thomas , Felix J. F. Herth , Manfred Dietel

DOI: 10.1007/S00428-012-1219-X

关键词: Sanger sequencingBiopsyMutation testingAlgorithmPulmonary adenocarcinomaEgfr mutationBiologyCarcinomaTyrosine-kinase inhibitorMutational status

摘要: … Based on the determined detection limit for EGFR mutations by Sanger sequencing we aimed to develop an algorithm for performing and reporting diagnostic analysis of NSCLC …

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