The Role of Syk in Cell Signaling
作者： Robert L. Geahlen , Debra L. Burg
DOI: 10.1007/978-1-4899-0987-9_11
关键词: Syk 、 Chemistry 、 Kinase 、 Tyrosine 、 Immune system 、 Transmembrane protein 、 Receptor 、 Phosphorylation 、 Cytoplasm 、 Cell biology
摘要: Many multichain antigen receptors on the surfaces of immune cells signal by stimulating phosphorylation key intracellular proteins tyrosine. This occurs even though transmembrane components themselves lack intrinsic enzymic activity. Instead, these associate with and through cytoplasmic proteintyrosine kinases. These kinases are now known to include members a new family for which prototype is recently discovered enzyme as p72 syk .
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