Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation.

作者: Yu-Chi Cheng , Li-Wen Chu , Jun-Yih Chen , Su-Ling Hsieh , Yu-Chin Chang

DOI: 10.3390/CELLS9091948

关键词: InflammationInflammasomeChemistrySchwann cellTXNIPProgrammed cell deathCell biologyPyroptosisViability assayLoganin

摘要: … Excessive generation of reactive oxygen species (ROS) and NOD-like receptor protein 3 (… Loganin’s effects were examined by CCK-8 assay, ROS assay, cell death assay, …

参考文章(68)
Myoung-Jin Kim, Gi-Sang Bae, Il-Joo Jo, Sun-Bok Choi, Dong-Goo Kim, Joon-Yeon Shin, Sung-Kon Lee, Min-Jun Kim, Soyoung Shin, Ho-Joon Song, Sung-Joo Park, Loganin protects against pancreatitis by inhibiting NF-κB activation European Journal of Pharmacology. ,vol. 765, pp. 541- 550 ,(2015) , 10.1016/J.EJPHAR.2015.09.019
Chan Hum Park, Takashi Tanaka, Ji Hyun Kim, Eun Ju Cho, Jong Cheol Park, Naotoshi Shibahara, Takako Yokozawa, Hepato-protective effects of loganin, iridoid glycoside from Corni Fructus, against hyperglycemia-activated signaling pathway in liver of type 2 diabetic db/db mice. Toxicology. ,vol. 290, pp. 14- 21 ,(2011) , 10.1016/J.TOX.2011.08.004
Rosalinda Madonna, Yong-Jian Geng, Harnath Shelat, Peter Ferdinandy, Raffaele De Caterina, High glucose-induced hyperosmolarity impacts proliferation, cytoskeleton remodeling and migration of human induced pluripotent stem cells via aquaporin-1 Biochimica et Biophysica Acta. ,vol. 1842, pp. 2266- 2275 ,(2014) , 10.1016/J.BBADIS.2014.07.030
Rongbin Zhou, Aubry Tardivel, Bernard Thorens, Inpyo Choi, Jürg Tschopp, Thioredoxin-interacting protein links oxidative stress to inflammasome activation Nature Immunology. ,vol. 11, pp. 136- 140 ,(2010) , 10.1038/NI.1831
Noriko Yamabe, Jeong Sook Noh, Chan Hum Park, Ki Sung Kang, Naotoshi Shibahara, Takashi Tanaka, Takako Yokozawa, Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice. European Journal of Pharmacology. ,vol. 648, pp. 179- 187 ,(2010) , 10.1016/J.EJPHAR.2010.08.044
Wei Ma, Kai-Jin Wang, Chen-Shu Cheng, Guo-qing Yan, Wei-Li Lu, Jing-Fang Ge, Yong-Xian Cheng, Ning Li, Bioactive compounds from Cornus officinalis fruits and their effects on diabetic nephropathy. Journal of Ethnopharmacology. ,vol. 153, pp. 840- 845 ,(2014) , 10.1016/J.JEP.2014.03.051
Kai Liu, Huiqin Xu, Gaohong Lv, Bin Liu, Maxwell Kim Kit Lee, Chunhong Lu, Xing Lv, Yunhao Wu, Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products Life Sciences. ,vol. 123, pp. 78- 85 ,(2015) , 10.1016/J.LFS.2014.12.028
S Dixit, A Maiya, Diabetic peripheral neuropathy and its evaluation in a clinical scenario: a review. Journal of Postgraduate Medicine. ,vol. 60, pp. 33- 40 ,(2014) , 10.4103/0022-3859.128805
V Sagulenko, S J Thygesen, D P Sester, A Idris, J A Cridland, P R Vajjhala, T L Roberts, K Schroder, J E Vince, J M Hill, J Silke, K J Stacey, AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC Cell Death & Differentiation. ,vol. 20, pp. 1149- 1160 ,(2013) , 10.1038/CDD.2013.37
Chan Mee Lee, Hyun Ah Jung, Sang Ho Oh, Chan Hum Park, Takashi Tanaka, Takako Yokozawa, Jae Sue Choi, Kinetic and molecular docking studies of loganin and 7- O -galloyl- d -sedoheptulose from Corni Fructus as therapeutic agents for diabetic complications through inhibition of aldose reductase Archives of Pharmacal Research. ,vol. 38, pp. 1090- 1098 ,(2015) , 10.1007/S12272-014-0493-3