Gastrointestinal function, morphology, and immune status in uremia.

摘要: Individuals with chronic renal failure (CRF) may have a variety of gastrointestinal (GI) problems, including dyspepsia, acid peptic disease, and bacterial overgrowth. We investigated function in 11 uremic patients, seven whom were on dialysis three times week four who not dialysis. Ten normal subjects studied as controls. The nutritional status the patients did differ from that control subjects. Seven demonstrated abnormal GI endoscopic findings, although none was severe; they also had prolonged oral-cecal transit but no evidence overgrowth, all numbers lymphocyte subpopulations within intestinal mucosa. significantly reduced activities mucosal sucrase maltase lactase. In spite reductions these enzymatic activities, carbohydrate malabsorption evident CRF group, probably because vast reserve small intestine. No differences noted between groups several peptidases. From data, we concluded is essentially postulate this normality, which contrast to previous related recent advances clinical management patients.