TRIM3, a tumor suppressor linked to regulation of p21 Waf1/Cip1

作者: Y Liu , R Raheja , N Yeh , D Ciznadija , A M Pedraza

DOI: 10.1038/ONC.2012.596

关键词: RNA interferenceCancer researchGrowth factorCyclinLoss of heterozygosityBiologyCDK inhibitorSuppressorPlatelet-derived growth factor receptorTRIM Family

摘要: … Consistent with this, reducing TRIM3 expression increased the incidence of and … Furthermore, TRIM3 can bind to the cdk inhibitor p21 WAF1/CIP1 . Thus, we conclude that TRIM3 is a …

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