Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.
作者： John Hwa , John Hwa , Dianne M Perez , Ming Ming Zhao
DOI:
关键词: Alpha-1 adrenergic receptor 、 Receptor 、 Ligand (biochemistry) 、 G alpha subunit 、 Agonist 、 Chemistry 、 Interleukin 10 receptor, alpha subunit 、 Liver X receptor alpha 、 Interleukin 5 receptor alpha subunit 、 Biochemistry
摘要: … alpha 1b-AR that converted the agonist binding profile entirely to that of the alpha 1a-AR when mutated to corresponding alpha … of antagonist selectivity between these two alpha 1-AR …
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