Laser fabrication of 3D gelatin scaffolds for the generation of bioartificial tissues
作者： Aleksandr Ovsianikov , Andrea Deiwick , Sandra Van Vlierberghe , Michael Pflaum , Mathias Wilhelmi
DOI: 10.3390/MA4010288
关键词: Materials science 、 Regeneration (biology) 、 Self-healing hydrogels 、 Tissue engineering 、 Adhesion 、 Gelatin 、 Polymerization 、 Biomedical engineering 、 Photopolymer 、 Methacrylamide
摘要: In the present work, two-photon polymerization (2PP) technique was applied to develop precisely defined biodegradable 3D tissue engineering scaffolds. The scaffolds were fabricated via photopolymerization of gelatin modified with methacrylamide moieties. results indicate that derivative (GelMod) preserves its enzymatic degradation capability after photopolymerization. addition, developed using 2PP support primary adipose-derived stem cell (ASC) adhesion, proliferation and differentiation into anticipated lineage.
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