Polymorphic Variation and Risk of Colorectal Cancer

作者: Richard A. Hubner , Richard S. Houlston

DOI: 10.1007/978-1-4419-6603-2_8

关键词: Developed countryBreast cancerMedicineDiseaseColorectal cancerInternal medicineAdvanced stageOncologyCancer

摘要: Colorectal cancer (CRC) is the third commonest worldwide after lung and breast cancer, two-thirds of CRCs occur in developed countries [1, 2]. Despite recent advances treatment prognosis for CRC patients with advanced stage disease remains poor, there an urgent need strategies to identify individuals increased risk so that colonoscopic screening chemoprevention can be directed those who will obtain most benefit [1].

参考文章(127)
Peter Beighton, Greta Beighton, de la Chapelle, A. The Person Behind the Syndrome. pp. 209- 209 ,(1997) , 10.1007/978-1-4471-0925-9_118
Simon G Thompson, Why and how Sources of Heterogeneity Should be Investigated Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition. pp. 157- 175 ,(2008) , 10.1002/9780470693926.CH9
N.H. Chapman, E.A. Thompson, Linkage disequilibrium mapping: the role of population history, size, and structure. Advances in Genetics. ,vol. 42, pp. 413- 437 ,(2001) , 10.1016/S0065-2660(01)42034-7
Neil J. Risch, Searching for genetic determinants in the new millennium Nature. ,vol. 405, pp. 847- 856 ,(2000) , 10.1038/35015718
Loïc Le Marchand, Timothy Donlon, Jean H. Hankin, Laurence N. Kolonel, Lynne R. Wilkens, Ann Seifried, B-vitamin intake, metabolic genes, and colorectal cancer risk (United States). Cancer Causes & Control. ,vol. 13, pp. 239- 248 ,(2002) , 10.1023/A:1015057614870
Sang-Geun Jang, Il-Jin Kim, Hio Chung Kang, Hye-Won Park, Sun-A Ahn, Hyun-Ju Yoon, Kun Kim, Hai-Rim Shin, Jin Soo Lee, Jae-Gahb Park, GSTT2 promoter polymorphisms and colorectal cancer risk BMC Cancer. ,vol. 7, pp. 16- 16 ,(2007) , 10.1186/1471-2407-7-16
Mark J. Ratain, Everett E. Vokes, Timothy M. Lestingi, Jacqueline Ramirez, Rosemarie Mick, Elora Gupta, Metabolic Fate of Irinotecan in Humans: Correlation of Glucuronidation with Diarrhea Cancer Research. ,vol. 54, pp. 3723- 3725 ,(1994)
Rolf H. Sijmons, Gerard J. te Meerman, Winette T. A. van der Graaf, Elisabeth G. E. de Vries, Robert M. W. Hofstra, Ilja M. Nolte, Mirjam M. de Jong, Jan H. Kleibeuker, Low-penetrance Genes and Their Involvement in Colorectal Cancer Susceptibility Cancer Epidemiology, Biomarkers & Prevention. ,vol. 11, pp. 1332- 1352 ,(2002)
Wade Samowitz, Bette Caan, Susan Neuhausen, Karen Curtin, Khe Ni Ma, Michael Hoffman, Martha L. Slattery, Associations among IRS1, IRS2, IGF1, and IGFBP3 Genetic Polymorphisms and Colorectal Cancer Cancer Epidemiology, Biomarkers & Prevention. ,vol. 13, pp. 1206- 1214 ,(2004)
Jia Chen, Edward Giovannucci, Karl Kelsey, Eric B Rimm, Meir J Stampfer, Graham A Colditz, Donna Spiegelman, Walter C Willett, David J Hunter, None, A Methylenetetrahydrofolate Reductase Polymorphism and the Risk of Colorectal Cancer Cancer Research. ,vol. 56, pp. 4862- 4864 ,(1996)