作者: B. J. CLAWSON
DOI: 10.1001/ARCHDERM.1931.03880230070008
关键词: Vaccine therapy 、 Surgery 、 Allergic state 、 Subcutaneous nodule 、 Medicine 、 Acute rheumatic fever 、 Subcutaneous injection
摘要: The therapy described in this paper was suggested by a series of experiments carried out studying the results treatment with vaccine animals made hypersensitive to streptococci an attempt find basis for acute rheumatic fever. These were (allergic) subcutaneous injection into one area agar at 45 C. heavily seeded streptococci. This method producing and maintaining allergic state had been demonstrated Swift. 1 In from twelve eighteen days after initial sensitizing dose, given injections previously used experimental rheumatoid nodules. 2 Into ten places on right side back each animal injected subcutaneously 11/100 standard amount left side,1/1,000 amount. former increasing