作者: G J M Garcia , G Mitchell , N Bailie , D Thornhill , J Watterson
DOI: 10.1088/1742-6596/85/1/012032
关键词: Pathology 、 Biomedical engineering 、 Nose 、 Breathing 、 Mucosal dryness 、 Nasal congestion 、 Medicine 、 Nasal airflow 、 Patient affected 、 Particle image velocimetry 、 Nasal cavity
摘要: The relationship between airflow patterns in the nasal cavity and function is poorly understood. This paper reports an experimental study of interplay symptoms a patient affected with atrophic rhinitis. pathology characterized by mucosal dryness, fetor, progressive atrophy anatomical structures, spacious cavity, paradoxical sensation congestion. A physical replica patient's geometry was made particle image velocimetry (PIV) used to visualize measure flow field. based on computed tomography (CT) scans built three steps: three-dimensional reconstruction CT scans; rapid prototyping cast; sacrificial use cast form model passage clear silicone. Flow were measured running water-glycerol mixture through evaluating displacement particles dispersed liquid using PIV. rate corresponded air representative human breathing at rest. trajectory observed left nose (more rhinitis) differed markedly from what considered normal, consistent epithelial damage cases condition. data are also useful for validation computational fluid dynamics predictions.