Organic base catalyzed O-alkylation of phenols under solvent-free condition

作者: Xiuli Bu , Huanwang Jing , Li Wang , Tao Chang , Lili Jin

DOI: 10.1016/J.MOLCATA.2006.06.009

关键词: Organic synthesisPhenolOrganic chemistryCatalysisPotassium carbonateAnhydrousChemistryAlkylationEtherOrganic basePhysical and Theoretical ChemistryProcess Chemistry and Technology

摘要: Several phenyl ethers were prepared under solvent-free condition at room temperature with good to excellent yields by simply grinding the mixture of relevant phenol, alkyl bromide, anhydrous potassium carbonate and organic base as catalyst in a mortar. This method is easy handle provides also convenient procedure for protecting phenols synthesis.

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