Dsc Screening for Drug-Drug Interactions in Poly Pharmaceuticals Intended for the Alleviation of the Symptoms of Colds and Flu. II.
作者： S. A. Botha , A. P. Lötter , J. L. Du Preez
DOI: 10.3109/03639048709040177
关键词: Pharmacology 、 Capsule Dosage Form 、 Salicylamide 、 Phenylephrine Hydrochloride 、 Ascorbic acid 、 Drug 、 Chemistry 、 Pyrilamine Maleate 、 Phenylephrine
摘要: AbstractDSC screening for drug-drug interactions of a polypharmaceutical capsule dosage form containing salicylaminde, ascorbic acid, pyrilamine maleate and phenylephrine hydrochloride was performed. The results show the following:1. Ascorbic acid is incompatible with salicylamide, pheynylephrine hydrochloride.2. Salicylamide hydrochloride.3. Pyrilamine salicylamide hydrochloride.4. Phenylephrine acid.
informapharmascience.com参考文章(2)
A.E. Troup, H. Mitchner, Degradation of Phenylephrine Hydrochloride in Tablet Formulations Containing Aspirin Journal of Pharmaceutical Sciences. ,vol. 53, pp. 375- 379 ,(1964) , 10.1002/JPS.2600530406
Sheldon Siegel, Roy H. Reiner, James A. Zelinskie, Edward J. Hanus, Tablets of Pyrilamine Resin Adsorbate with Aspirin and Vitamin C Journal of Pharmaceutical Sciences. ,vol. 51, pp. 1068- 1071 ,(1962) , 10.1002/JPS.2600511112