Myocardial release of lactate, hypoxanthine, and urate during and following percutaneous transluminal coronary angioplasty. Potential mechanism for the generation of free radicals

摘要: Until recently the assessment of alteration in myocardial metabolism man early after an abrupt occlusion a major coronary artery has not been feasible. PTCA however, now provides unique opportunity to study time course these metabolic changes during transient interruption flow by balloon sequence patients with single-vessel disease and without angiographically demonstrable collateral circulation (1, 2). The need detect any persisting or mechanical dysfunction becomes even greater concern as number dilated vessels duration inflation tend increase, thereby enhancing both extent severity ischemia. risk exists that damage induced intervention may exceed its benefit.