Lipolytic effects of heparin and low molecular weight heparin and their importance in hemodialysis.

摘要: The incidence and the degree of uremic hypertriglyceridemia in a hemodialysis population are exacerbated by use UF heparin as anticoagulant therapy. This is associated with an increase levels triglyceride-rich remnant particles that thought to be particularly atherogenic. Since arteriosclerosis its related diseases major causes morbidity mortality this dialysis population, LMW heparins their reduced stimulation plasma lipolytic activity may provide clinically superior alternative for anticoagulation therapy long-term hemodialysis. One also speculate it more advantageous all treatments heparin.