AGE-SPECIFIC DIFFERENCES IN DURATION OF CLINICAL PROTECTION AFTER VACCINATION WITH MENINGOCOCCAL POLYSACCHARIDE A VACCINE
作者： ArthurL Reingold , AllenW Hightower , GailA Bolan , EllenE Jones , Hilaire Tiendrebeogo
DOI: 10.1016/S0140-6736(85)90224-7
关键词: Group A 、 Vaccination 、 Immunology 、 El Niño 、 Vaccine efficacy 、 Meningococcal vaccine 、 Internal medicine 、 Meningitis 、 Bacterial vaccine 、 MENINGOCOCCAL POLYSACCHARIDE 、 Medicine
摘要: Abstract Sequential case-control studies were used to monitor changes in the clinical protection induced by group A meningococcal polysaccharide vaccine over a 3-year period. Overall, efficacy declined from 87% 1 year after vaccination 70% and 54% at 2 3 years, respectively. When stratified age time of data showed that, although remained high children ≥4 years (vaccine 85%, 74%, 67% 1, 2, vaccination, respectively), it dramatically those
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