Right ventricular dysfunction, late gadolinium enhancement, and female gender predict poor outcome in patients with dilated cardiomyopathy

作者: Christina Doesch , Désirée-Marie Dierks , Dariusch Haghi , Rainer Schimpf , Jürgen Kuschyk

DOI: 10.1016/J.IJCARD.2014.09.004

关键词: Right ventricular dysfunctionHeart failureLate gadolinium enhancementMedicineDilated cardiomyopathyRisk stratificationInternal medicineIn patientRight ventricular ejection fractionCardiologyMagnetic resonance imaging

摘要: Abstract Aims Dilated cardiomyopathy (DCM) shows a variable disease course and is associated with significant morbidity mortality. So far, left ventricular function (LVF) the major determinant for risk stratification. However, since it has shown to be poor guide individual outcome, we studied prognostic value of cardiovascular magnetic resonance imaging (CMR) parameters, late gadolinium enhancement (LGE) epicardial adipose tissue (EAT). Methods results 140 patients DCM underwent CMR. During median follow-up 3years, 22 (16%) died another 51 (36%) were hospitalized due congestive heart failure (CHF). Female gender right ejection fraction (RV-EF) below 38% independent predictors all-cause mortality in multivariable analysis. In who CHF, RV-EF was only predictor When where further stratified according systolic LV-EF, predict cardiac remained unchanged. Looking at during compared those former presented higher prevalence LGE as well reduced indexed EAT. Conclusion gender, presence are importance DCM. Therefore, present study underlines role CMR an important tool stratification

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