Iodine promoted α-hydroxylation of ketones
作者： Yogesh Siddaraju , Kandikere Ramaiah Prabhu
DOI: 10.1039/C5OB00684H
关键词: Organic chemistry 、 Chemistry 、 α hydroxylation 、 Aryl 、 Iodine
摘要: A novel method for α-hydroxylation of ketones using substoichiometric amount iodine under metal-free conditions is described. This has been successfully employed in synthesizing a variety heterocyclic compounds, which are useful precursors. α-Hydroxylation diketones and triketones illustrated. strategy provides novel, efficient, mild inexpensive aryl sub-stoichiometric molecular iodine.
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