Metronidazole and drug resistance.
作者： P.J. Johnson
DOI: 10.1016/0169-4758(93)90143-4
关键词: Microbiology 、 Drug 、 Anaerobic bacteria 、 Trichomonas 、 Giardia 、 Biology 、 Bacteroides 、 Metronidazole 、 Clostridium 、 Drug resistance
摘要: … Further evidence sup porting this mode of activation includes studies showing that inhibitors of gly colysis block drug activation and that the rate of metronidazole reduction is severely …
elsevier.com
sci-hub.se 参考文章(43)
Miklós Müller, Mode of action of metronidazole on anaerobic bacteria and protozoa Surgery. ,vol. 93, pp. 165- 171 ,(1983) , 10.5555/URI:PII:0039606083902957
S N Moreno, R P Mason, R Docampo, Distinct reduction of nitrofurans and metronidazole to free radical metabolites by Tritrichomonas foetus hydrogenosomal and cytosolic enzymes. Journal of Biological Chemistry. ,vol. 259, pp. 8252- 8259 ,(1984) , 10.1016/S0021-9258(17)39721-1
H.L. Callahan, S.M. Beverley, Heavy metal resistance: a new role for P-glycoproteins in Leishmania. Journal of Biological Chemistry. ,vol. 266, pp. 18427- 18430 ,(1991) , 10.1016/S0021-9258(18)55077-8
R Marczak, T E Gorrell, M Müller, Hydrogenosomal ferredoxin of the anaerobic protozoon, Tritrichomonas foetus. Journal of Biological Chemistry. ,vol. 258, pp. 12427- 12433 ,(1983) , 10.1016/S0021-9258(17)44193-7
Francis J.C. Roe, Toxicologic evaluation of metronidazole with particular reference to carcinogenic, mutagenic, and teratogenic potential. Surgery. ,vol. 93, pp. 158- 164 ,(1983) , 10.5555/URI:PII:0039606083902945
J D Santangelo, D T Jones, D R Woods, Metronidazole activation and isolation of Clostridium acetobutylicum electron transport genes. Journal of Bacteriology. ,vol. 173, pp. 1088- 1095 ,(1991) , 10.1128/JB.173.3.1088-1095.1991
E. Knight, R. W.F. Hardy, Flavodoxin CHEMICAL AND BIOLOGICAL PROPERTIES Journal of Biological Chemistry. ,vol. 242, pp. 1370- 1374 ,(1967) , 10.1016/S0021-9258(18)96101-6
S N Moreno, R P Mason, R P Muniz, F S Cruz, R Docampo, Generation of free radicals from metronidazole and other nitroimidazoles by Tritrichomonas foetus. Journal of Biological Chemistry. ,vol. 258, pp. 4051- 4054 ,(1983) , 10.1016/S0021-9258(18)32579-1
M. Ouellette, F. Fase-Fowler, P. Borst, The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene. The EMBO Journal. ,vol. 9, pp. 1027- 1033 ,(1990) , 10.1002/J.1460-2075.1990.TB08206.X
J. G. Lossick, B. L. Miklos Muller, T. E. Gorrell, In vitro drug susceptibility and doses of metronidazole required for cure in cases of refractory vaginal trichomoniasis. The Journal of Infectious Diseases. ,vol. 153, pp. 948- 955 ,(1986) , 10.1093/INFDIS/153.5.948