Proteomic Approaches for Studying the Phases of Wound Healing

作者: Laura E. Edsberg

DOI: 10.1007/978-3-642-00534-3_15

关键词: MedicineWound healingBioinformaticsDelayed healingProteomeChronic woundDiseaseCell specificNegative-pressure wound therapyProteomics

摘要: Proteome level information is necessary to understand the function of specific cell types and their roles in health disease. Proteomics a rapidly developing field with wide range applications wound healing. The ability use proteomics assess healing process would have many benefits, including earlier evidence better understanding how different treatments affect at protein level. basis what known about chronic proteome based on results from broad collection studies utilizing number proteomic techniques fluids tissues wounds etiologies. identification biomarkers associated or delayed could great significance current treatments, as well development new therapeutic interventions.

参考文章(46)
Simona Vittorini, Simona Storti, Maria Serena Parri, Alfredo Giuseppe Cerillo, Aldo Clerico, SERCA2a, Phospholamban, Sarcolipin, and Ryanodine Receptors Gene Expression in Children with Congenital Heart Defects Molecular Medicine. ,vol. 13, pp. 105- 111 ,(2007) , 10.2119/2006-00054.VITTORINI
Sudhir Srivastava, Informatics In Proteomics CRC Press. ,(2005) , 10.1201/9781420027624
Harold Brem, Olivera Stojadinovic, Robert F. Diegelmann, Hyacinth Entero, Brian Lee, Irena Pastar, Michael Golinko, Harvey Rosenberg, Marjana Tomic-Canic, Molecular markers in patients with chronic wounds to guide surgical debridement. Molecular Medicine. ,vol. 13, pp. 30- 39 ,(2007) , 10.2119/2006-00054.BREM
Olivera Stojadinovic, Harold Brem, Constantinos Vouthounis, Brian Lee, John Fallon, Michael Stallcup, Ankit Merchant, Robert D. Galiano, Marjana Tomic-Canic, Molecular pathogenesis of chronic wounds: The role of β-catenin and c-myc in the inhibition of epithelialization and wound healing American Journal of Pathology. ,vol. 167, pp. 59- 69 ,(2005) , 10.1016/S0002-9440(10)62953-7
Anamika M. Rasik, Arti Shukla, Antioxidant status in delayed healing type of wounds. International Journal of Experimental Pathology. ,vol. 81, pp. 257- 263 ,(2001) , 10.1046/J.1365-2613.2000.00158.X
M.L. Fernandez, J.A. Broadbent, G.K. Shooter, J. Malda, Z. Upton, Development of an enhanced proteomic method to detect prognostic and diagnostic markers of healing in chronic wound fluid. British Journal of Dermatology. ,vol. 158, pp. 281- 290 ,(2007) , 10.1111/J.1365-2133.2007.08362.X
Eleanor J. Barone, Dome R. Yager, Andrea L. Pozez, Oluyinka O. Olutoye, Mary C. Crossland, Robert F. Diegelmann, Kelman I. Cohen, Interleukin-1alpha and collagenase activity are elevated in chronic wounds Plastic and Reconstructive Surgery. ,vol. 102, pp. 1023- 1027 ,(1998) , 10.1097/00006534-199809020-00015
Lillian B. Nanney, Robert L. Caldwell, Alonda C. Pollins, Nancy L. Cardwell, Susan R. Opalenik, Jeffrey M. Davidson, Novel approaches for understanding the mechanisms of wound repair. The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. ,vol. 11, pp. 132- 139 ,(2006) , 10.1038/SJ.JIDSYMP.5650002
Mike Tyers, Matthias Mann, From genomics to proteomics Nature. ,vol. 422, pp. 193- 197 ,(2003) , 10.1038/NATURE01510