Reducing rates of preventable HIV/AIDS-associated mortality among people living with HIV who inject drugs.

作者: Surita Parashar , Alexandra B. Collins , Julio S.G. Montaner , Robert S. Hogg , Michael-John Milloy

DOI: 10.1097/COH.0000000000000297

关键词: CriminalizationAcquired immunodeficiency syndrome (AIDS)PopulationSocial stigmaSubstance abuseMedicineHuman immunodeficiency virus (HIV)Psychological interventionEnvironmental healthDrug

摘要: Purpose of review The modern antiretroviral therapy (ART) era has seen substantial reductions in mortality among people living with HIV. However, HIV-positive who inject drugs (PWIDs) continue to experience high rates suboptimal HIV-related outcomes. We recent findings regarding factors contributing premature and preventable PWID, describe the promise interventions improve survival this group. Recent current leading causes death PWID are HIV/AIDS-related causes, overdose, liver-related including infection hepatitis C virus. Elevated levels population driven by social-structural barriers ART access adherence, particularly criminalization stigmatization drug use. In contexts where opioid substitution adherence support programs widely accessible, evidence highlights comparable HIV do not drugs. Summary life-saving benefits can be realized when it is paired strategies that address evidence-based medical care. Joint administration therapy, as well repeal punitive laws criminalize users, urgently needed reduce injection-related PWID.

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