The relationship between shocks and survival in out-of-hospital cardiac arrest patients initially found in PEA or asystole

作者: Al Hallstrom , Thomas D. Rea , Vince N. Mosesso , Leonard A. Cobb , Andy R. Anton

DOI: 10.1016/J.RESUSCITATION.2007.02.003

关键词: CardiologyAsystoleDefibrillationInternal medicineVentricular fibrillationResuscitationElectrocardiographyRandomized controlled trialIntensive carePulseless electrical activitySurgeryMedicine

摘要: Summary Objective To describe survival rates from out-of-hospital cardiac arrest for patients who present with pulseless electrical activity or asystole according to whether they remained in a non-shockable rhythm converted ventricular fibrillation and were shocked appropriately. Methods Design: Observational analysis of registry collected as part randomized trial. Setting: Five urban/suburban cities the United States Canada. Participants: Trial subjects (adult, treated, non-traumatic) whose first documented heart rhythm/state following was activity. Intervention: Periodic pauses assess shockable rhythm. Main outcome measure: Survival hospital discharge. Results Of 1377 patients, 738 presented an initial either asystole. 738, 78% (n = 574) subsequently at each evaluation throughout resuscitation (No-Shock group) while 22% (n = 164) by emergency medical service (Shock group). discharge significantly greater No-Shock group (4.9% versus 0.6%, p = 0.01). Shock predictor (odds ratios = 0.18, p = 0.036) death after adjustment potential confounders. Conclusions These results suggest that develop VF during course treatment initially observed do not benefit conventional approaches such defibrillation. Further study is warranted define optimal this patient cohort.

参考文章(13)
Thomas D. Rea, Mickey S. Eisenberg, Greg Sinibaldi, Roger D. White, Incidence of EMS-treated out-of-hospital cardiac arrest in the United States Resuscitation. ,vol. 63, pp. 17- 24 ,(2004) , 10.1016/J.RESUSCITATION.2004.03.025
Ting Yu, Max Harry Weil, Wanchun Tang, Shijie Sun, Kada Klouche, Heitor Povoas, Joe Bisera, Adverse outcomes of interrupted precordial compression during automated defibrillation Circulation. ,vol. 106, pp. 368- 372 ,(2002) , 10.1161/01.CIR.0000021429.22005.2E
Yoji Sato, Max Harry Weil, Shijie Sun, Wanchun Tang, Jianlin Xie, Marko Noc, Joe Bisera, Adverse effects of interrupting precordial compression during cardiopulmonary resuscitation. Critical Care Medicine. ,vol. 25, pp. 733- 736 ,(1997) , 10.1097/00003246-199705000-00005
J HERLITZ, L EKSTROM, B WENNERBLOM, A AXELSSON, A BANG, S HOLMBERG, Prognosis Among Survivors of Prehospital Cardiac Arrest Annals of Emergency Medicine. ,vol. 25, pp. 58- 63 ,(1995) , 10.1016/S0196-0644(95)70356-X
Wanchun Tang, David Snyder, Jinglan Wang, Lei Huang, Yun-Te Chang, Shijie Sun, Max Harry Weil, One-Shock Versus Three-Shock Defibrillation Protocol Significantly Improves Outcome in a Porcine Model of Prolonged Ventricular Fibrillation Cardiac Arrest Circulation. ,vol. 113, pp. 2683- 2689 ,(2006) , 10.1161/CIRCULATIONAHA.105.592121
Robert A. Berg, Arthur B. Sanders, Karl B. Kern, Ronald W. Hilwig, Joseph W. Heidenreich, Matthew E. Porter, Gordon A. Ewy, Adverse Hemodynamic Effects of Interrupting Chest Compressions for Rescue Breathing During Cardiopulmonary Resuscitation for Ventricular Fibrillation Cardiac Arrest Circulation. ,vol. 104, pp. 2465- 2470 ,(2001) , 10.1161/HC4501.098926
Christie Atwood, Mickey S. Eisenberg, Johan Herlitz, Thomas D. Rea, Incidence of EMS-treated out-of-hospital cardiac arrest in Europe Resuscitation. ,vol. 67, pp. 75- 80 ,(2005) , 10.1016/J.RESUSCITATION.2005.03.021
Anouk P van Alem, Björn T Sanou, Rudolph W Koster, Interruption of cardiopulmonary resuscitation with the use of the automated external defibrillator in out-of-hospital cardiac arrest Annals of Emergency Medicine. ,vol. 42, pp. 449- 457 ,(2003) , 10.1067/S0196-0644(03)00383-4