Cell wall turnover in growing and nongrowing cultures of Bacillus subtilis.

摘要: Cell wall turnover was studied in cultures of Bacillus subtilis which growth inhibited by nutrient starvation or the addition antibiotics. Concomitantly, synthesis wall, as measured incorporation radioactively labeled N-acetylglucosamine, followed some these cultures. In potassium- phosphate-starved cultures, stopped, but continued at a rate slightly lower than that control Lysis cells did not occur. glucose-starved caused lysis cells, since apparently inhibited. The same phenomenon observed after arrest inhibitors such fosfomycin, cycloserine, penicillin G, and vancomycin. Growth chloramphenicol allowed continuation synthesis; therefore, generally cause cell lysis.