Plasma cholecystokinin response to oral fat in patients with Billroth I and Billroth II gastrectomy.

摘要: The present study was undertaken to determine whether bypassing the duodenum in patients with Billroth II gastrectomy affects plasma cholecystokinin (CCK) release response ingestion of fat. Plasma CCK concentrations were measured by radioimmunoassay using two antibodies; antibody 1703 binds all carboxyl-terminal CCK-peptides containing at least 14 amino acid residues, while T204 is specific for sulphated tyrosine region CCK. There no significant differences among fasting seven (1.3 +/- 0.4 fmol/ml, 1703; 2.6 T204), six I (0.6 0.3 2.9 0.5 and nine normal subjects (0.7 0.1 1.9 T204). Ingestion 250 ml 20% Intralipid induced similar increases (11.2 2.0 10.1 2.4 T204) as (11.8 8.4 1.1 However, increments (11.5 1.4 9.3 significantly (p less than 0.01) greater those (4.7 0.8 4.1 0.7 fmol/ml). Similarly, integrated secretion (510 58 fmol/ml X 120 min, 458 69 (457 143 365 61 0.05) (230 49 162 24 It concluded that oral fat partial subjects, have after