Postoperative Pain Relief Using Intermittent Injections of 0.5% Ropivacaine Through a Catheter After Laparoscopic Cholecystectomy

作者: Anil Gupta , Sven E. Thörn , Kjell Axelsson , Lars G. Larsson , Göran Ågren

DOI: 10.1213/00000539-200208000-00040

关键词: AnesthesiaMedicineSurgeryCholecystectomyRopivacaineKetobemidonePlaceboLocal anestheticAmbulatoryVisual analogue scalePropofolAnesthesiology and Pain Medicine

摘要: Postoperative pain has been an important limiting factor for ambulatory laparoscopic cholecystectomy. We anesthetized 40 ASA physical status I–II patients using propofol the induction and sevoflurane in oxygen air maintenance of anesthesia. At end anesthesia, were randomized into one two groups: Group P (Placebo) R (0.5% Ropivacaine). Twenty milliliters normal saline or ropivacaine, respectively, injected intraperitoneally at surgery via a catheter placed bed gall bladder. Postoperatively, intermittent injections (10 mL) study solution given when required pain. Ketobemidone 1–2 mg was IV as rescue medication. Pain assessed visual analog scale 1, 2, 3, 4, 8, 12, 16, 20 h after once each day 1 wk rest (deep pain), shoulder incision sites, during coughing. Recovery by time to transfer from Phase ability walk, drink, eat, void. Plasma concentrations ropivacaine measured eight patients. Time defecation, driving car, return activities also recorded through questionnaire sent home with patient. During first 4 postoperative h, had lower scores deep coughing compared (P 0.05). No differences found consumption ketobemidone. Median times recovery similar between groups. By seventh day, 93% returned daily living. conclude that early cholecystectomy could be relieved 0.5%

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