Risk factors for duration of equine rhinitis A virus respiratory disease

摘要: Background Infectious respiratory disease is common in young horses and can impact athletic performance long-term health. Significant variation the duration of clinical has been observed, even absence secondary complications. The determination factors associated with chronicity may facilitate decision-making development improved biosecurity protocols. Objective To investigate contact network characteristics, demographic variables time to recovery from Equine Rhinitis A virus disease. Study design Prospective cohort study. Methods Yearling Standardbred racehorses (n = 58) housed a multi-barn training facility Southern Ontario were included. Horses monitored daily for signs acute over 41-day period Autumn 2017. Contact patterns between horses, including older racehorses, determined through use proximity loggers attached halters during initial 7-day Associations disease, (birth month, gait, sex yearling sale), serologic titres metrics (degree, betweenness Eigenvector centrality) investigated using Cox proportional hazard model. Results attack rate infectious was 87.9% 51). Median 6 days (IQR 1-32) 17 censored due early withdrawal or failure recover study period. In those yearlings born February-May, birth month significant model (Hazard Ratio 0.7, 95% CI 0.49-1, P 0.05). Main limitation Probability censoring not independent outcome which necessitated sensitivity analysis. Conclusions These findings suggest late foals are less likely quickly