Prospective Randomized Comparative Evaluation of Proximal Valve Polyurethane and Distal Valve Silicone Peripherally Inserted Central Catheters

摘要: Purpose The objective of this study was to evaluate and compare the relative durability complications between proximal valve polyurethane distal silicone peripherally inserted central catheters (PICCs). Methods Institutional review board approval obtained. A total 326 patients (mean age, 50.4 years) assigned randomly receive either a PICC ( n = 198) or Groshong 194). All PICCs were under radiologic guidance by interventional radiologists. Follow-up data collected until catheter removal because treatment completion. Results mean dwell time 25.6 days (range, 1–245 days). Complications encountered in 26.8% 47.9% PICCs, respectively P .003) catheter-related infection (6.2% versus 2%, 0.043) noted PICCs. No significant differences incidence occlusion, fracture, dislodgement found. Multivariate logistic regression analysis showed higher complication rate corrected for patients' sex, underlying morbidity, indication, peripheral vein accessed, arm used, tip placement, number venepunctures attempted. Conclusions Proximal more durable than which associated with phlebitis infection, probably related materials designs placements valves.