Pneumopathie interstitielle non spécifique : une nouvelle entité anatomoclinique au sein des pneumopathies interstitielles diffuses idiopathiques

摘要: Nonspecific interstitial pneumonitis with fibrosis has been individualized within the group of idiopathic diffuse pneumonias by pathological criteria. It is differentiated from usual temporal uniformity lesions, a prominent inflammatory infiltration, and absence honeycombing. Clinical functional symptoms are those pneumonitis. An etiology may be found in about half cases, including connective tissue disease, exposure to organic antigens, or recent acute lung injury. Computed tomography chest shows bilateral ground glass opacities, alveolar opacities peribronchiolar patchy distribution. Prognosis rather good, since majority patients improve when treated corticosteroids an association immunosuppressive drugs. These etiologic prognostic features justify individualization nonspecific as distinct clinicopathological entity.