Feasibility and safety of percutaneous coronary intervention in patients with end-stage liver disease referred for liver transplantation

作者: Babak Azarbal , Paul Poommipanit , Boris Arbit , Antoine Hage , Jignesh Patel

DOI: 10.1002/LT.22301

关键词: Internal medicineCoronary artery diseaseLiver diseaseMyocardial infarctionConventional PCIMedicinePercutaneous coronary interventionPacked red blood cellsAngioplastyCardiologySurgeryLiver transplantationHepatologyTransplantation

摘要: Percutaneous coronary intervention (PCI) has traditionally not been an option for patients with end-stage liver disease (ESLD) and artery (CAD). This retrospective study was designed to demonstrate the feasibility safety of PCI in transplant candidates. Patients ESLD hemodynamically significant CAD who were otherwise deemed be acceptable candidates transplantation underwent PCI. The procedural success rates, mortality myocardial infarction bleeding outcomes examined. Sixteen PCI: 15 bare-metal stents (1.3 per patient on average) 1 balloon angioplasty alone. median diameter stenosis lesion 80%, platelet count 68 × 10(9) /L, international normalized ratio 1.3, Model End-Stage Liver Disease score 13. successful 94% patients. One had a suboptimal residual 50% after stenting. There no in-hospital or 30-day deaths infarctions, developed hematomas. required 1-U transfusion, another U packed red blood cells. All remained clinically stable month Nine 16 listed transplantation, 3 transplantation. In conclusion, we have demonstrated small cohort CAD, majority whom thrombocytopenia. Larger studies are determine whether is effective treatment strategy would

参考文章(33)
Don Poldermans, Olaf Schouten, Radosav Vidakovic, Jeroen J Bax, Ian R Thomson, Sanne E Hoeks, Harm HH Feringa, Martin Dunkelgrün, Peter de Jaegere, Alexander Maat, Marc RHM van Sambeek, Miklos D Kertai, Eric Boersma, DECREASE Study Group, A Clinical Randomized Trial to Evaluate the Safety of a Noninvasive Approach in High-Risk Patients Undergoing Major Vascular Surgery: The DECREASE-V Pilot Study Journal of the American College of Cardiology. ,vol. 49, pp. 1763- 1769 ,(2007) , 10.1016/J.JACC.2006.11.052
Jaime Bosch, Juan Carlos García-Pagán, Complications of cirrhosis. I. Portal hypertension Journal of Hepatology. ,vol. 32, pp. 141- 156 ,(2000) , 10.1016/S0168-8278(00)80422-5
Farzan Filsoufi, Sacha P. Salzberg, Parwis B. Rahmanian, Thomas D. Schiano, Hussien Elsiesy, Anthony Squire, David H. Adams, Early and late outcome of cardiac surgery in patients with liver cirrhosis Liver Transplantation. ,vol. 13, pp. 990- 995 ,(2007) , 10.1002/LT.21075
Elliott Antman, Jean-Pierre Bassand, Werner Klein, Magnus Ohman, Jose Luis Lopez Sendon, Lars Rydén, Maarten Simoons, Michal Tendera, Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. Journal of the American College of Cardiology. ,vol. 36, pp. 959- 969 ,(2000) , 10.1016/S0735-1097(00)00804-4
D.A. Diedrich, J.Y. Findlay, B.A. Harrison, C.B. Rosen, Influence of coronary artery disease on outcomes after liver transplantation. Transplantation proceedings. ,vol. 40, pp. 3554- 3557 ,(2008) , 10.1016/J.TRANSPROCEED.2008.08.129
Jeffrey S. Plotkin, R. Michael Benitez, Paul C. Kuo, Mary J. Njoku, Linda A. Ridge, James W. Lim, Charles D. Howell, Jacqueline M. Laurin, Lynt B. Johnson, Dobutamine stress echocardiography for preoperative cardiac risk stratification in patients undergoing orthotopic liver transplantation Liver Transplantation. ,vol. 4, pp. 253- 257 ,(1998) , 10.1002/LT.500040415
WILLIAM D. CAREY, JOHN A. DUMOT, RONNIE R. PIMENTEL, DAVID S. BARNES, ROBERT E. HOBBS, J. MICHAEL HENDERSON, DAVID P. VOGT, JAMES T. MAYES, MARY KAY WESTVEER, KIRK A. EASLEY, The prevalence of coronary artery disease in liver transplant candidates over age 50. Transplantation. ,vol. 59, pp. 859- 864 ,(1995) , 10.1097/00007890-199503000-00010
Ron Waksman, Spencer B. King, John S. Douglas, Yannan Shen, Heather Ewing, Lorena Mueller, Ziyad M.B. Ghazzal, William S. Weintraub, Predictors of groin complications after balloon and new-device coronary intervention American Journal of Cardiology. ,vol. 75, pp. 886- 889 ,(1995) , 10.1016/S0002-9149(99)80681-X
Abdel Aziz M. Shaheen, Gilaad G. Kaplan, James N. Hubbard, Robert P. Myers, Morbidity and mortality following coronary artery bypass graft surgery in patients with cirrhosis: a population-based study Liver International. ,vol. 29, pp. 1141- 1151 ,(2009) , 10.1111/J.1478-3231.2009.02058.X