Bacterial Genome Annotation
作者： Nicholas Beckloff , Shawn Starkenburg , Tracey Freitas , Patrick Chain
DOI: 10.1007/978-1-61779-827-6_16
关键词: Genome 、 Genome evolution 、 Annotation 、 Genome project 、 Gene 、 Biology 、 Computational biology 、 Vertebrate and Genome Annotation Project 、 Function (biology) 、 Bacterial genome size
摘要: Annotation of prokaryotic sequences can be separated into structural and functional annotation. Structural annotation is dependent on algorithmic interrogation experimental evidence to discover the physical characteristics a gene. This done in an effort construct accurate gene models, so understanding function or evolution genes among organisms not impeded. Functional sequence similarity other known proteins assess Combining across genomes comparative manner promotes higher levels as well advanced genome evolution. As availability bacterial increases methods improve, value will increase.
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