Preparation and characterization of chitosan/sepiolite bionanocomposites for tetracycline release
作者： Emel Gür , Aylin Altinisik , Kadir Yurdakoc
DOI: 10.1002/PC.23751
关键词: Chitosan 、 Thermogravimetric analysis 、 Materials science 、 Silanol 、 Composite material 、 Point of zero charge 、 Sepiolite 、 Thermal stability 、 Fourier transform infrared spectroscopy 、 Scanning electron microscope
摘要: Chitosan/sepiolite (CS/SEP) bionanocomposite films have been prepared and characterized with Fourier transform infrared spectroscopy, thermogravimetric analysis (TGA), X-ray diffraction, scanning electron microscopic analysis. The results indicated the formation of a phase separated microcomposite structure at low high content SEP. point zero charge was determined as neutral pH. thermal behavior samples examined by TGA/derivative (DTG) dispersed clay improved stability matrix systematically increase loading. release Tetracycline (TC) also studied in batch system function pH, content, contact time 37°C. Increase composite resulted decrease TC due to interaction silanol groups (SiOH) OH drug hydrogen bonding. Diffusion rate aqueous medium decreased increasing SEP content. POLYM. COMPOS., 2015. © 2015 Society Plastics Engineers
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