The utility of preoperative endometrial sampling for the detection of uterine sarcomas

作者: Nisha Bansal , Thomas J. Herzog , William Burke , Carmel J. Cohen , Jason D. Wright

DOI: 10.1016/J.YGYNO.2008.02.026

关键词: Endometrial biopsyEndometrial stromal sarcomaHysterectomyLeiomyosarcomaPreoperative careRadiologyEndometrial cancerGynecologyMedicineUterine sarcomaSampling (medicine)

摘要: Abstract Objective Uterine sarcomas are aggressive cancers, often not recognized prior to surgical exploration. The goal of this study was determine the utility endometrial sampling in detecting uterine and examine factors associated with diagnostic inaccuracy. Methods All tumors identified at hysterectomy from 1990 2006 were reviewed. Included patients underwent preoperative reviewed our center. Pathologic data documented through review hospital records. Statistical analysis performed using Chi square test. Results 938 identified. Preoperative available for 730 (78%) subjects. occurred 142 patients; 72 (51%) sampling. Overall, an invasive tumor 84% (600/713), correct histology 79% (564/713). Among women sarcomas, suggested 86% (62/72) predicted histologic diagnosis 64% (46/72). rate detection cancer by statistically different among epithelial (86% vs. 84%, p =0.76). significantly less reliable predicting (64% 81%, =0.84). Conclusions Endometrial has a lower predictive value diagnosing compared malignancies. Biopsy curettage have similar accuracy. Novel techniques needed accurately identify preoperatively.

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