RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations

作者: Brice Laffleur , Uttiya Basu , Junghyun Lim

DOI: 10.1016/J.JMB.2016.12.021

关键词: GeneCell biologySomatic hypermutationBiologyNon-coding RNARNA silencingExosome complexMessenger RNAGeneticsExosome Multienzyme Ribonuclease ComplexDNA

摘要: … , to produce high-affinity IgE antibodies (direct class switching from μ to ε is also possible). All … has to be investigated in different models (because CH12F3 cells can only switch to IgA). …

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