Hypertension after kidney transplantation

摘要: Abstract Background: Few studies have examined the possible role of blood pressure (BP), independent acute rejection and graft function, on outcomes after kidney transplantation. Methods: We investigated prevalence, treatment, control, clinical correlates hypertension its association with outcomes, using multivariate analyses time-dependent covariates, in a retrospective cohort 1,666 transplant recipients. Results: Hypertension was common, control poor. For example, at 1 year, only 55.5% had BP less than 140 mm Hg. Control improved slightly 1993–2002 compared to 1976–2002, even as patients administered 2 or more antihypertensive medications year increased from 43.5% 54.6%. Independent higher included male sex, age, donor diabetes, body mass index, presence native kidneys, delayed function. Previous associated virtually all times transplantation, these associations were estimated creatinine clearance (C Cr ). Conversely, an between subsequent not statistically significant when differences C taken into account. After adjusting for effects rejection, , other variables, each 10 Hg systolic relative risk failure (1.12; 95% confidence interval, 1.08 1.15; P