Molecular Basis of the Activity of Antibiotics of the Vancomycin Group: Guides for Peptide–Peptide Binding

摘要: Publisher Summary Antibiotics of the vancomycin group have assumed increasing clinical importance because prevalence Staphylococcus aureus bacteria, which are resistant to methicillin. This chapter discusses that itself has found extensive use in treatment postoperative diarrhea, caused by Clostridium difficile gut. The antibiotic is then given orally, and been be very efficient curing a dangerous condition. As antibiotics this increased, pharmaceutical companies many parts world initiated efforts find new members. result, now consists large number structures, all heptapeptides. For produced any one actinomycete, there often variants, frequently differing nature attached sugars or fatty acid groups. Proton resonances its free form, when bound cell wall analogue, assigned specific protons structure.