Systemic lupus erythematosus. Follow-up study of 148 patients. II: Predictive factors of importance for course and outcome.

摘要: The predictive value of a number clinical and laboratory variables for the mortality 148 patients with systemic lupus erythematosus (SLE) mean observation period 8 years 10-year-survival 80 per cent was calculated by means differentiated survival rate analyses stepwise regression analyses. power several increased if calculations were based on deaths caused SLE rather than total rate. decreased after 1973 because diagnosis made in some terminal disease who would have remained without before that time. causes death treatment identical 1973. presence high diagnostic ARA criteria within first year predictor survival. Severe but non-fatal infections (meningitis, septicemia, pneumonia) significantly reduced Patients proteinuria azotemia, 2 observation, had 70 cent. CNS manifestations not reduced. butterfly rash lymphopenia predictors survival, whereas DNA antibodies no