General practitioners choose within a narrow range of drugs when initiating new treatments: a cohort study of cardiovascular drug formularies.

作者: Allan Buusman , Jakob Kragstrup , Morten Andersen

DOI: 10.1007/S00228-005-0973-Y

关键词: FormularyDrugSurgeryCohort studyPrescription dataGeneral practiceMedical prescriptionEmergency medicineNarrow rangeMedicineCardiovascular drug

摘要: The aims of this study were (1) to develop and evaluate a new method for investigating personal drug formularies in general practice (2) test the hypothesis that there is difference between incident ongoing use. In 2002, we studied prescribing patterns beta-blockers, calcium channel blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin-II antagonists statins County Funen, Denmark (180 practices, 472,000 inhabitants). For each practice, distinguished an formulary consisting prescriptions users including patients already treatment. Prescription data retrieved from Odense University Pharmacoepidemiologic Database (OPED). Four different measures evaluated used comparing General practitioners’ (GPs’) comprised significantly fewer drugs than their all groups except antagonists. total number was 1.8 3.3. We found differences 0.5 1.6 analogues DU 90% (number accounting prescribed volume measured defined daily doses) segment selectivity index 0.05 0.12. preference most analogue 9–18% higher among patients. highly correlated with other quantified both range skewed distribution choice. Analysing GPs’ simple inexpensive studying own current formularies. GPs choose within narrow

参考文章(19)
Gaist D, Hallas J, Sørensen Ht, The Danish prescription registries. Danish Medical Bulletin. ,vol. 44, pp. 445- 448 ,(1997)
M McCarthy, K Wilson-Davis, H McGavock, Relationship between the number of partners in a general practice and the number of different drugs prescribed by that practice. British Journal of General Practice. ,vol. 42, pp. 10- 12 ,(1992)
Jane Robertson, Jayne L. Fryer, Dianne L. O'Connell, Anthony J. Smith, David A. Henry, Personal formularies. An index of prescribing quality European Journal of Clinical Pharmacology. ,vol. 57, pp. 333- 341 ,(2001) , 10.1007/S002280100310
K Wilson-Davis, H McGavock, J P Connolly, Repeat prescribing management--a cause for concern? British Journal of General Practice. ,vol. 49, pp. 343- 347 ,(1999)
C M Bond, R J Taylor, Change in the established prescribing habits of general practitioners: an analysis of initial prescriptions in general practice. British Journal of General Practice. ,vol. 41, pp. 244- 248 ,(1991)
C. S. de Vries, N. M. van Diepen, T. F. J. Tromp, L. T. W. Jong-van den Berg, Auditing GPs’ prescribing habits: cardiovascular prescribing frequently continues medication initiated by specialists European Journal of Clinical Pharmacology. ,vol. 50, pp. 349- 352 ,(1996) , 10.1007/S002280050121
U. Bergman, C. Popa, Y. Tomson, B. Wettermark, T. R. Einarson, H. Åberg, F. Sjöqvist, Drug utilization 90% - a simple method for assessing the quality of drug prescribing European Journal of Clinical Pharmacology. ,vol. 54, pp. 113- 118 ,(1998) , 10.1007/S002280050431
U. Bergman, M. Andersen, A. Vaccheri, L. Bjerrum, N. Montanaro, B. Wettermark, Deviations from evidence-based prescribing of non-steroidal anti-inflammatory drugs in three European regions European Journal of Clinical Pharmacology. ,vol. 56, pp. 269- 272 ,(2000) , 10.1007/S002280000144
N. Britten, S. Brant, A. Cairns, W. W. Hall, I. Jones, C. Salisbury, A. Virji, A. Herxheimert, Continued prescribing of inappropriate drugs in general practice. Journal of Clinical Pharmacy and Therapeutics. ,vol. 20, pp. 199- 205 ,(1995) , 10.1111/J.1365-2710.1995.TB00649.X